Hare Krishna Environment LLP

Chemical and Physical Properties

• Molecular Formula: C₈H₁₇NO₂
• Molecular Weight: 159.23 g/mol
• Chemical Name: (S)-3-(aminomethyl)-5-methylhexanoic acid (an S-enantiomer and GABA analogue)
• Solubility: Soluble in water (clear at roughly 2 mg/mL or higher depending on grade/assay specifications)
• Melting Point: Approximately 86°C to 88°C (359.3 K)

Pregabalin powder is a white to off-white crystalline API (Active Pharmaceutical Ingredient) used to manufacture capsules, tablets, and oral solutions for treating neuropathic pain, epilepsy, and anxiety. Chemically a gabapentinoid (), it binds to Calcium channels to reduce neural excitability. It requires controlled, dry storage

Pharmacology and Uses

• Classification: Analgesic, anticonvulsant, and anxiolytic agent acting as a calcium channel blocker.
• Mechanism: Binds to the α₂δ subunit of voltage-gated calcium channels in the central nervous system to reduce the release of excitatory neurotransmitters.
• Therapeutic Applications: Used to formulate medications for neuropathic pain (such as diabetic peripheral neuropathy and postherpetic neuralgia), epilepsy/partial-onset seizures, fibromyalgia, and generalized anxiety disorder.